I bought and tried Smart Scroll and it doesn't work with the Targus Mouse.
I like the mouse, but no driver works correctly yet.
The Apple Mighty Mouse has 360 degree scrolling as doesn't the track pad, but nothing works with the Targus yet.
It can scroll up and down OR left and right, but not both. There is no diagonal scroll.
I hate the scroll ball on the Mighty Mouse and the way the right and left clicks work.
The Targus Mouse is a much better design if someone could just get the drivers working.