It didn't work out of the box for me, but I'm not familiar with this network.
Not even slightly Macintosh like. No menu bar. Copy and paste don't work in most places.
Not that bad once you get it going. The Kad search worked best
Found 3 copies of something I had been looking for without success on gnutella and bittorrent.
I'm only getting single digit KB/s download speeds at best.
Upload speed is whatever I set it to, so some people are getting good download speeds, just not me :-)

I'm not sure if I recomment aMule or not. VersionTracker won't let me leave that blank.
The best thing is that it connects to another independent network that is very much alive and well.