My version of THPS 4 says 1.0.6, but VersionTracker doesn't go that high, so hope this works for you... To get the program to run in Leopard without crashing right away, copy (don't move) this folder:
System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchServices.framework
to this location:
System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks
I just dug deep into the crash report and made some observations, tried a few things, and this worked! Even on my Intel iMac! Awesome game!