I was a long-time user of Eudora but had to give it up when it started refusing to print messages. I then decided to give Mailsmith a go, and stuck with it for about a month until its sluggishness began to drive me completely crazy. Then I switched to GyazMail and I have found it to be just what I need to process the sometimes thousands of e-mails which I receive daily from a number of organizational accounts. Used with SpamSieve, the junk-mail filtering is top-notch. Another feature which I really like, is the ability to select a large number of messages and redirect them all to another address; this can be done in Eudora, but can not be done in Mailsmith without extra scripting.