If you're having problems running Shion and have installed Indigo in the past, you need to remove a bit of software that Indigo installs into your system that prohibits other applications (such as Shion) from accessing your Insteon hardware. See

http://www.audacious-software.com/forums/comments.php?DiscussionID=2&page=1

My apologies for the inconvenience, and I'll be adding a detector for this file in the next release of the application.