I've been using create for a number of years. At first I bought it because I couldn't afford InDesign, but now I can't afford to use create because it's so freak'n slow. I use InDesign when I need to design/layout with graphics.

I use create for converting anything to web read jpgs, flow charts, or anything SIMPLE. Because if you throw an image over 10mb in create, create almost goes into limp mode. Like I said, it's a great app, but you need to know it's limitations.