AnaBuilder now has an excellent GUI, although you will need to read some documentation to understand the buttons, even with the pop-up button descriptions. This is to be expected; In a word processor, we have all learned what they can do, and most programs work in a similar way. AnaBuilder is new and we don't have much experience with similar programs. One interface oddity: There is one window. If you close it, the program quits.
I have tried to build anaglyphs in Photoshop, and they don't look great. All you have to do is put the red channel from one picture into the other picture, then align the points to be at the monitor depth, and crop. But alignment is no always easy, and colors can cause things to appear black in on eye, and white in the other. AnaBuilder has tools to desaturate reds and blues so they don't distract your eyes. It has many other useful tools as well.
(To the authors: Thanks for your work. Versiontracker is used by some ungrateful people who love to criticize. Pay no attention.)