I got a total of over 2000 downloads (cumulative total for OligoChecker 2 on MacOS X and MacOS 9 with about 90% on MacOS X). According to Gartner the Mac has a worldwide market share of 1.8% (3.2 in the US) - so I would expect about 20-30 times as many downloads for the Windows version when it becomes available (40,000 – 60,000 (?) ... although 20,000 seems a more realistic total to me). Now if one assumes 20,000 people using the program and saving on average just 15 min a week (not counting other savings), then the cumulative total in saved working hours each week is 5,000 h (the equivalent of 125 full-time positions each year!) ... time which surely could be spend on more interesting research :-)