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Sequencher - 4.9

DNA sequence analysis.

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Current Version:	4.9
Release Date:	2009-04-01
License:	Update
Downloads (this version):	650
Downloads (all versions):	3,602

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Product Description:

Sequencher works with all automated DNA sequencers and is widely known for its lightning-fast contig assembly, short learning curve, user-friendly editing tools, and superb technical support. First released almost 15 years ago, Sequencher is currently used for sequence analysis tasks in every major genomic and pharmaceutical company as well as numerous academic and government labs in over 40 countries around the world. Life Science researchers use Sequencher for many diverse DNA sequence analysis applications including de novo gene sequencing, mutation detection, forensic human identification, systematics, and more. Sequencher capabilities include heterozygote & SNP detection and analysis, cDNA to Genomic DNA large gap alignment, comparative sequencing, support for confidence scores, ORF translation, GenBank feature import, and restriction enzyme mapping.

What's new in this version:

Translated Variance Table - The Translated Variance Table summarizes all amino acid differences in a selected set of samples. Because the table is linked to the underlying sequence data, it is ideal for validating mutations that result in changes to the amino acid translation and for checking expression vectors.
Filter the Results of the Variance Tables - You can restrict your Variance Table to just coding sequence, or just variants, or exons, or genes, or any region specified with a feature. Similarly you can define a Translation Range, even across multiple introns, for the Translated Variance Table.
Reports - Sequencher's new reporting creates printable versions of your data. The Reports provide analysis tools such as clustering of like samples in the Population Report and calculating the percentage of secondary peak heights in the Variance Detail Report.
SuperPro Key support - We replaced the purple Eve3 key with the fully supported blue or black and blue SuperPro key. This change increases the compatibility of Macintosh standalone licenses on newer Macintosh operating systems.
Improved Sequence Features - Sequencher now imports GenBank features with complex locations, such as the joined and ordered locations that are common in exon and mRNA features. Sequencher also has improved tools for the import and annotation of complemented features.
Enhancements to the Variance Table - We have added more tools to enhance the utility of the Variance Table. From column selections you can now label, add comments to, and get info from samples. You can also selectively remove columns from the table as you work.
Better Translation Tools - The Reference translation now updates as you edit, and a new option forces the frame of the consensus translation to correspond to the Reference. Sequence Editors will now translate joined features even when they are separated by non-coding sequence.
Contextual Menus - You can invoke context-sensitive menus in some Sequencher windows by using the right-mouse click on Windows and right-mouse click or Ctrl+click on Mac.

Operating System Requirements:

This product is designed to run on the following operating systems:

Mac OS X 10.5 Intel
Mac OS X 10.5 PPC
Mac OS X 10.4 Intel
Mac OS X 10.4 PPC
Mac OS X 10.3.9

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