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CLC Main Workbench - 5.5

Protein and dna sequence analyses.

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Current Version:	5.5
Release Date:	2009-10-08
License:	Update
Downloads (this version):	242
Downloads (all versions):	9,443

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Product Description:

This 4-week fully functional demo of CLC Combined Workbench aggregates all DNA sequence analyses of CLC Gene Workbench and all protein sequence analyses of CLC Protein Workbench. All analyses are fully integrated in one single, user-friendly, and intuitive software application. Some analyses are

Assembly of DNA sequencing data
Advanced primer design
Molecular cloning
Fully integrated 1D DNA Gel Simulator
Automatic SNP annotation of sequences
Secondary protein structure prediction
Integrated 3D molecular view
Signal Peptide Prediction (SignalP)
Transmembrane helix prediction (TMHMM)
Protein family analysis (PFAM)
2 types of alignments
Phylogenetics
Motif search (known patterns)
Motif search using regular expressions
Motif search using ProSite patterns
Pattern discovery (unknown patterns)
Web based BLAST
BLAST on local databases
Batch processing of multiple analyses in one work-step
Dot plots
Hydrophobicity analyses
Antigenicity analyses
Searches on GenBank, SwissProt, TrEMBL, and PubMed
Detailed log of actions/analyses performed

What's new in this version:

Gateway cloning. Simple and easy-to-use support for creating Gateway entry and expression clones.
Search for matches among all your saved primers. The Find Binding Sites tool has been greatly improved to now allow you to search among all your primers. In addition, you also get a tabular output of the binding sites and possible fragments.
In silico PCR: create PCR product based on primer pair and template sequence (including primer extensions). As part of the improved Find Binding Sites and Create Fragments tool, you can extract the PCR product from the list of fragments through a right-click menu.
Check primer specificity. As part of the improved Find Binding Sites and Create Fragments tool, you can search with a primer pair in a list of potential target sequences and see an overview table of binding sites and mismatches as well as potential PCR fragments.
Various bug fixes

Operating System Requirements:

This product is designed to run on the following operating systems:

Mac OS X 10.5 Intel
Mac OS X 10.5 PPC
Mac OS X 10.4 Intel
Mac OS X 10.4 PPC

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