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 AmplifX - 1.5.0test, manage and design primers for PCR |
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Product Description:
The main purpose of AmplifX is to seek in a collection of primers, such as any molecular biologist get in his refrigerators, those which can be use to amplify a fragment into a target sequence, for example, and particularly, to design strategies to screen recombinant clones by PCR. Some informations are associated with each primer, some automatically computed by AmplifX (like TM, Quality, lengh) and other given by the user (name, comments,...) This allows general aspects of primer management (sequences and real tubes). AmplifX can also design new primers.
What's new in this version:
- Modification of primer list format (automatically updated when open with AmplifX 1.5.0 or superior).
- To work on a shared primer collection into a team or a lab, the best way is to use the same primer list file into the local network. To help working in this way, now, AmplifX manages a locking system that allow only the first user to write into the primer list and save changes. The other users can only read the file and must "save as..." if they make some changes. After the first user close the file, the lock is destroyed and one other user can reload the modified primer list and make its own changes.
- A new column "Owner" is especially useful in the context of shared primer list. Its entry is made easier by a scrolling menu.
- Heights and widths of the columns of the primer list and size and position of the main window are restored at each launching of AmplifX.
- To each new added primer, an id is automatically created (it can be changed by hand, of course). The program analyses previous ids and increment them: they can be constructed with any prefix and a number possibly formatted with a constant number of digits: example Pr0001, Pr0002,...
- End of line characters are forbidden into any primer list fields: Enter and Return keys are managed in the same way as the tab key: editing of the next field.
- Add amplicon size information into found primer pairs of the Primer design window.
- The primer design window is not resizable anymore.
- Management of expiration date for the beta releases of AmplifX.
- Drag and drop is now properly managed into the target sequence text field: dragging from an outside source (text editor, web page) insert recognized ATGC (upper and lower cases) at the insertion point. But dragging from the target sequence field itself is forbidden. Because it has appeared to be triggered accidentally (while playing with selection for example.
- Automatic fetch for AmplifX updates.
- Automatic request for registration (after using AmplifX for a while) by an integrated form. (Note: registering and giving some feedback is not very time consuming but very motivating and interesting for the kind developer that improve this program in his free time.)
- Fixing paste function in the search dialog and in the ID and description of the primer list.
- Fixing zoom function triggered by the drag + cap key: the zoomed map is well centered on the dragged region.
Operating System Requirements:
This product is designed to run on the following operating systems:
- Mac OS X 10.4 Intel
- Mac OS X 10.4 PPC
- Mac OS X 10.3.9
- Mac OS X 10.3
- Mac OS X 10.2
Additional Requirements:
- Mac OS X 10.4 PPC
- Mac OS X 10.3.9
- Mac OS X 10.4 Intel
- Mac OS X 10.0
- Mac OS X 10.1
- Mac OS X 10.5 PPC
- Mac OS X 10.2
- Mac OS X 10.5 Intel
- Mac OS X 10.3
- Mac OS Classic
Screenshots:
Download Links:
Download AmplifX Now (File Size: 3.5M)
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Featured Reviews
Over tall buildings - Version: 1.1, 2/7/2005 07:50PM PST
(0 of 5 users found this comment useful)
Duckhue
Over my head. Maybe it will help get accurate tests for Lyme Disease. One can only hope.
Most Recent Replies: View All 1 Replies
- Over tall buildings
Very nice indeed!!! 
- Version: 0.96, 11/23/2004 09:08AM PST
(2 of 2 users found this comment useful)
Cortig
This is a very nice application. The day it does everything Amplify did, I dump Classic from my Mac (I still use Amplify from time to time). Simple to use, fast and efficient. I love it :-)
Great way to intuitively check your primers - Version: 0.92, 11/3/2004 03:59AM PST
(2 of 2 users found this comment useful)
younghart_1
This little app comes in handy if you want to start a PCR on a new sequence. After entering your sequence and loading (or entering) the primers you consider useful, you will get a graphic overview of the resulting PCR products, along with Tm values for your primers from all 3 major calculation methods, probable primer-dimer formations, scores, ...
While still in an early stage, this app has the potential to become an invaluable tool in molecular biology. Has a slim interface, no clutter, and if you know what Polymerase Chain Reaction is about, you understand AmplifX within minutes.
While still in an early stage, this app has the potential to become an invaluable tool in molecular biology. Has a slim interface, no clutter, and if you know what Polymerase Chain Reaction is about, you understand AmplifX within minutes.
