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Mac Classic  |  Math/Scientific  |  OligoChecker

OligoChecker

OligoChecker - 2.40

Organize & better utilize oligos in the lab, run PCR.

All Time: Not rated (0.0)
This Version: Not rated (0.0)
Current Version: 2.40
Release Date: 2009-08-19
License: Shareware
Downloads (this version): 597
Downloads (all versions): 3,382
Price: $19.95

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Product Description:

Do you have a print-out of your sequence with the position of the primers penciled in?

Are you using Excel to maintain a list of your oligos?

Have you just moved from working on one gene to working on a similar one and wonder which primers you can still use for your PCR?

Do you subclone and rearrange sequences and somewhere along the line lost track on which primer to use where?

Have you started in a new lab, inherited a box of oligos and a folder full of printouts that came with them but no information on what they were ordered for?

Have you ordered and waited for primers because you don't know which of the ones available you can use with your sequence?

If any of these sound familiar then OligoChecker might be for you.

What's new in this version:

2.40
  • Layout: increased description field so that more text can be displayed
  • Layout: moved oligo order info to the right, made it hideable
  • Fix: some users experienced redraw artefacts where some controls were improperly drawn on screen in the oligo window
  • Fix: application name displays the short form now (it showed the platform it was compiled for)

Operating System Requirements:

This product is designed to run on the following operating systems:

  • Mac OS Classic

Additional Requirements:

  • Mac OS 8.5 - 9.2.2

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OligoChecker Developer Notea little anecdote ... - Version: 2.9.5, 2/1/2005 02:33AM PST

MarkusWinter
as my girlfriend started her new job as research associate she brought an Excel spreadsheet with the oligo data from her new lab with her. We transferred the 145 oligos into OligoChecker in just under 3 minutes using the Excel template. Her boss had designed some oligos to introduce mutations into a sequence so we ran the oligos against the sequence - they look fine EXCEPT THERE ARE NO MISMATCHES IN THE ALIGNMENT! The oligos her boss designed and bought are not mutagenic! Time saved before the mistake would have been discovered by sequencing the "mutated" plasmid: about a week. Money saved: about $1,000. :-)
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OligoChecker Developer Notea little anecdote ... - Version: 2.9.5, 2/1/2005 02:33AM PST

MarkusWinter
... as my girlfriend started her new job as research associate she brought an Excel spreadsheet with the oligo data from her new lab with her. We transferred the 145 oligos into OligoChecker in just under 3 minutes using the Excel template. Her boss had designed some oligos to introduce mutations into a sequence so we ran the oligos against the sequence - they look fine EXCEPT THERE ARE NO MISMATCHES IN THE ALIGNMENT! The oligos her boss designed and bought are not mutagenic! Time saved before the mistake would have been discovered by sequencing the "mutated" plasmid: about a week. Money saved: about $1,000. :-)
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OligoChecker Developer NoteAfter just 3 weeks ... - Version: 2.8, 11/1/2004 04:12AM PST

MarkusWinter
I got a total of over 2000 downloads (cumulative total for OligoChecker 2 on MacOS X and MacOS 9 with about 90% on MacOS X). According to Gartner the Mac has a worldwide market share of 1.8% (3.2 in the US) - so I would expect about 20-30 times as many downloads for the Windows version when it becomes available (40,000 – 60,000 (?) ... although 20,000 seems a more realistic total to me). Now if one assumes 20,000 people using the program and saving on average just 15 min a week (not counting other savings), then the cumulative total in saved working hours each week is 5,000 h (the equivalent of 125 full-time positions each year!) ... time which surely could be spend on more interesting research :-)
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