OligoChecker - 2.40Organize & better utilize oligos in the lab, run PCR. |
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a little anecdote ... - Version: 2.9.5, 2/1/2005 02:33AM PST
MarkusWinter
as my girlfriend started her new job as research associate she brought an Excel spreadsheet with the oligo data from her new lab with her. We transferred the 145 oligos into OligoChecker in just under 3 minutes using the Excel template. Her boss had designed some oligos to introduce mutations into a sequence so we ran the oligos against the sequence - they look fine EXCEPT THERE ARE NO MISMATCHES IN THE ALIGNMENT! The oligos her boss designed and bought are not mutagenic! Time saved before the mistake would have been discovered by sequencing the "mutated" plasmid: about a week. Money saved: about $1,000. :-)
a little anecdote ... - Version: 2.9.5, 2/1/2005 02:33AM PST
MarkusWinter
... as my girlfriend started her new job as research associate she brought an Excel spreadsheet with the oligo data from her new lab with her. We transferred the 145 oligos into OligoChecker in just under 3 minutes using the Excel template. Her boss had designed some oligos to introduce mutations into a sequence so we ran the oligos against the sequence - they look fine EXCEPT THERE ARE NO MISMATCHES IN THE ALIGNMENT! The oligos her boss designed and bought are not mutagenic! Time saved before the mistake would have been discovered by sequencing the "mutated" plasmid: about a week. Money saved: about $1,000. :-)
After just 3 weeks ... - Version: 2.8, 11/1/2004 04:12AM PST
MarkusWinter
I got a total of over 2000 downloads (cumulative total for OligoChecker 2 on MacOS X and MacOS 9 with about 90% on MacOS X). According to Gartner the Mac has a worldwide market share of 1.8% (3.2 in the US) - so I would expect about 20-30 times as many downloads for the Windows version when it becomes available (40,000 – 60,000 (?) ... although 20,000 seems a more realistic total to me). Now if one assumes 20,000 people using the program and saving on average just 15 min a week (not counting other savings), then the cumulative total in saved working hours each week is 5,000 h (the equivalent of 125 full-time positions each year!) ... time which surely could be spend on more interesting research :-)